Publication type
Journal Article
Authors
Publication date
July 15, 2018
Summary:
Deprived neighbourhoods have long been associated with poorer health outcomes. However, many quantitative studies have not evidenced the mechanisms through which place ‘gets under the skin’ to influence health. The increasing prevalence of biosocial data provides new opportunities to explore these mechanisms and incorporate them into models of contextual effects. The stress pathway is a key biosocial mechanism; however, few studies have explicitly tested it in neighbourhood associations. This paper addresses this gap by investigating whether allostatic load, a biological response to chronic stress, mediates relationships of neighbourhood deprivation to physical and mental health. Data from UK Understanding Society is used to undertaken a multilevel mediation analysis. Allostatic load is found to mediate the association between neighbourhood deprivation and health, substantiating the biological mechanism of the stress pathway. More deprived areas are associated with higher allostatic load, and in turn worse allostatic load relates to poorer physical and mental health. Allostatic load is a stronger mediator of physical health than mental health, suggesting the stress pathway is more pertinent to explaining physical health gradients. Heterogeneity in the results between physical and mental health suggests more research is needed to disentangle the biosocial processes that could be important to health and place relationships.
Published in
Health and Place
Volume and page numbers
Volume: 52 , p.25 -33
DOI
https://doi.org/10.1016/j.healthplace.2018.05.003
ISSN
13538292
Subjects
Notes
Referenced by: Understanding Society (2018) ‘Written evidence from Understanding Society the UK Household Longitudinal Study (WSN0051) [Work and Pensions Select Committee. Welfare safety net inquiry]’. London: Great Britain. Parliament. House of Commons. Work and Pensions Select Committee.
Open Access
Open Access funded by Economic and Social Research Council
Under a Creative Commons license
#525075