Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Publication type

Journal Article

Authors

Publication date

October 11, 2017

Summary:

High blood pressure is the foremost heritable global risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits to date (systolic, diastolic, pulse pressure) in over one million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also reveal shared loci influencing lifestyle exposures. Our findings offer the potential for a precision medicine strategy for future cardiovascular disease prevention.

Published in

bioRxiv

DOI

https://doi.org/10.1101/198234

Subjects

Notes

The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission.

#524942

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