Job insecurity and risk of diabetes: a meta-analysis of individual participant data

Publication type

Journal Article

Authors

Publication date

December 15, 2016

Summary:

Background: Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes. Methods: We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate. Results: The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09-1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01-1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I2 = 24%, p = 0.2; multivariable-adjusted model: I2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04-1.35). Interpretation: Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity.

Published in

CMAJ:Canadian Medical Association Journal

Volume and page numbers

Volume: 188 , p.447 -455

DOI

http://dx.doi.org/10.1503/cmaj.150942

ISSN

8203946

Subjects

Notes

Covered by over 15 media outlets worldwide

#523930

---

Related Publications

• Job insecurity tied to increased risk of diabetes

  1. Jane E. Ferrie
  2. Marianna Virtanen
  3. Markus Jokela
  4. Ida E.H. Madsen
  5. Katriina Heikkilä
  6. Lars Alfredsson
  7. G. David Batty
  8. Jakob B. Bjorner
  9. Marianne Borritz
  10. Hermann Burr
  11. Nico Dragano
  12. Marko Elovainio
  13. Eleonor I. Fransson
  14. Anders Knutsson
  15. Markku Koskenvuo
  16. Aki Koskinen
  17. Anne Kouvonen
  18. Meena Kumari
  19. Martin L. Nielsen
  20. Maria Nordin
  21. Tuula Oksanen
  22. Krista Pahkin
  23. Jan H. Pejtersen
  24. Jaana Pentti
  25. Paula Salo
  26. Martin J. Shipley
  27. Sakari B. Suominen
  28. Adam Tabák
  29. Töres Theorell
  30. Ari Väänänen
  31. Jussi Vahtera
  32. Peter J.M. Westerholm
  33. Hugo Westerlund
  34. Reiner Rugulies
  35. Solja T. Nyberg
  36. Mika Kivimäki

  Media
  October 4, 2016