Skip to content

Journal Article

The role of material, psychosocial and behavioral factors in mediating the association between socioeconomic position and allostatic load (measured by cardiovascular, metabolic and inflammatory markers)

Authors

Publication date

Mar 2015

Summary

Lower socioeconomic position (SEP), both accumulated across the life course and at different life-stages, has been found to be associated with higher cumulative physiological burden, as measured by allostatic load. This study aimed to identify what factors mediate the association between SEP and allostatic load, as measured through combining cardiovascular, metabolic and inflammatory markers. We explored the role of material, psychological and behavioral factors, accumulated across two periods in time, in mediating the association between SEP and allostatic load. Data are from the West of Scotland Twenty-07 Study, with respondents followed over five waves of data collection from ages 35 to 55 (n = 999). Allostatic load was measured by summing nine binary biomarker scores (‘1’ = in the highest-risk quartile) measured when respondents were 55 years old (wave 5). SEP was measured by a person’s accumulated social class over two periods All mediators and SEP were measured at baseline in 1987 and 20 years later and combined to form accumulated measures of risk. Material mediators included car and home ownership, and having low income. The General Health Questionnaire (GHQ-12) was used as the psychosocial mediator. Behavioral mediators included smoking, alcohol consumption, physical activity and diet. Path analysis using linear regressions adjusting for sex were performed for each of the potential mediators to assess evidence of attenuation in the association between lower SEP and higher allostatic load. Analyses by mediator type revealed that renting one’s home (approximately 78% attenuation) and having low income (approx. 62% attenuation) largely attenuated the SEP–allostatic load association. GHQ did not attenuate the association. Smoking had the strongest attenuating effect of all health behaviors (by 33%) with no other health behaviors attenuating the association substantially. Material factors, namely home tenure and income status, and smoking have important roles in explaining socioeconomic disparities in allostatic load, particularly when accumulated over time.

Published in

Brain, Behavior, and Immunity

Volume and page numbers

45 , 41 -49

DOI

http://dx.doi.org/10.1016/j.bbi.2014.10.005

ISSN

16

Subjects

Income Dynamics, Health, Life Course Analysis, Social Stratification, and Biology

Links

http://repository.essex.ac.uk/12660/

Notes

Copyright © 2014 Published by Elsevier Inc.; Open Access article; Open Access funded by Medical Research Council

#522794


Research home

Research home

News

Latest findings, new research

Publications search

Search all research by subject and author

Podcasts

Researchers discuss their findings and what they mean for society

Projects

Background and context, methods and data, aims and outputs

Events

Conferences, seminars and workshops

Survey methodology

Specialist research, practice and study

Taking the long view

ISER's annual report

Themes

Key research themes and areas of interest