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Journal Article

Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study

Authors

Publication date

Feb 2013

Summary

Objective: To examine the effects of pregnancy planning, time to conception (TTC), and assisted reproductive technologies (ART) on child behavior. Design: Prospective cohort study. Setting: Not applicable. Patient(s): A total of 12,380 singletons recruited at 9 months and followed-up at 5 and 7 years. Conceptions were divided into "unplanned" (unplanned, unhappy), "mistimed" (unplanned, happy), "planned" (planned, TTC < 12 months), "subfertile" (planned, TTC >= 12 months), "ovulation induced" (received clomiphene citrate), and "ART" (IVF or intracytoplasmic sperm injection). Intervention(s): None. Main Outcome Measure(s): Child behavior (Strengths and Difficulties Questionnaire [SDQ]). Result(s): Mistimed and unplanned children had higher average SDQ scores at age 5 and 7 years and were significantly more likely to have a clinically relevant behavioral problem compared with the planned group. The ART children had significantly higher average SDQ scores at both 5 and 7 years compared with the planned group. An increase in clinically relevant behavioral problems was observed at 5 years (odds ratio 2.05 [95% confidence interval 0.96, 4.42]) but failed to reach statistical significance. No effects were observed in the subfertile and ovulation-induced groups. Conclusion(s): Unplanned and mistimed children exhibit more behavioral problems than their planned peers. Though ART children have higher mean total difficulties scores, this did not translate into a statistically significant increase in clinically relevant behavioral problems. (Fertil Steril (R) 2013; 99: 456-63. (C) 2013 by American Society for Reproductive Medicine.)

Published in

Fertility and Sterility

Volume and page numbers

99 , 456 -463

DOI

http://dx.doi.org/10.1016/j.fertnstert.2012.10.029

ISSN

16

Subjects

Child Development and Childbearing: Fertility

Notes

Not held in Res Lib - bibliographic reference only

#521512


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